Host-Microbiome Interactions in Neurodevelopment and Gut-Brain Barriers

Welcome to the Aburto Lab

We are interested in understanding how alterations of perinatal factors, such as gut microbes, modulate neurodevelopment at cellular and molecular levels. How do the highly diverse microbial signals interact at the different barriers across the gut-brain axis? How does that impact the developing brain? We answer these questions harnessing different mouse models of perinatal gut microbiota disruption and other models of host genetics-environment interactions.

We are part of the Brain-Gut-Microbiota Axis in APC Microbiome Ireland and the Department of Anatomy and Neuroscience at University College Cork. We work in close collaboration with Prof. John F. Cryan and Prof. Gerard Clarke at UCC.