Host-Microbiome Interactions in Neurodevelopment and Gut-Brain Barriers

Welcome to the Aburto Lab

We are interested in understanding how alterations of factors across the lifespan, such as gut microbes, modulate neurovascular development and function at cellular and molecular levels. How do the highly diverse microbial signals interact at the different barriers across the gut-brain axis? How does that impact the developing brain? How does that impact brain function in the context of neuropsychiatric disorders? We answer these questions harnessing different mouse models of gut microbiota disruption across the lifespan and other models of host genetics-environment interactions.

We are part of the Brain-Gut-Microbiota Axis in APC Microbiome Ireland and the Department of Anatomy and Neuroscience at University College Cork.